TABLE 8.
Candidate genes
| Chromo- some | QTa | cM | Gene | Name of product |
|---|---|---|---|---|
| 4 | C | 52 | Bmfr1 | B-cell maturation factor responsiveness 1 |
| 54.1 | Ckb-rs1 | Creatine kinase; brain; related sequence 1 | ||
| 57.2 | Grik3 | Glutamate receptor; ionotropic; kainate 3 | ||
| 5 | C | 19 | Nos3 | Nitric oxide synthase 3 |
| 17 | Il6 | Interleukin-6 | ||
| 20 | Fgfr3 | Fibroblast growth factor receptor 3 | ||
| 22 | Hs3st1 | Heparan sulfate 3-O-sulfotransferase 1 | ||
| 14 | C | 45 | Tnfsf11 | TNF superfamily member 11 |
| 53.5 | Irg1 | Immunoresponsive gene 1 | ||
| 59 | Fgf14 | Fibroblast growth factor 14 (FHF4) | ||
| 12 | C, E | 58-59 | Igh | Immunoglobulin heavy chain complex |
| 13 | C, E | 33 | Fgfr4 | Fibroblast growth factor receptor 4 |
| 35 | Il9 | Interleukin-9 | ||
| 10 | E | 40.9 | Mif | Macrophage migration inhibitory factor |
| 47 | Timp3 | Tissue inhibitor of MMP3 | ||
| 48 | Igf1 | Insulin-like growth factor 1 | ||
| 52 | Cradd | Caspases Rip adaptor with death domain | ||
| 67 | Ifng | Interferon gamma | ||
| 17 | E | 45 | Lamr9 | Laminin receptor 9 |
| 46.5 | Lhcgr | Choriogonadotropin receptor |
a
QT, qualitative trait; C, clinical disease; E, histopathology in the eye.