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. 2006 Jan;13(1):14–17. doi: 10.1101/lm.60406

Figure 3.

Figure 3.

(A) Extinction training: Freezing behavior (mean ± s.e.m.) during the first minute preceding the first CS-alone presentation (BL, baseline) and during CS-alone presentations (45 trials averaged in five trial blocks) in rats that received pre-training combined lesions of the medial prefrontal cortex and the motor cortex (MO + mPFC) (n = 8), the septal area (SEP + mPFC) (n = 8), or the mediodorsal thalamus (MD + mPFC) (n = 5), and sham-operated (SH) (n = 7) and un-operated (UN-OP) (n = 23) rats. (B) Retention test: Freezing behavior (mean ± s.e.m.) during each CS-alone presentation (five trials) in subjects operated on before conditioning (PRE) or after extinction (POST) (MO + mPFC, n = 7; SEP + mPFC, n = 6; MD + mPFC, n = 6; SH, n = 4). The NO-EXT group (n = 15) represents rats that were also operated on before conditioning (PRE; n = 7) or after extinction (POST) (n = 8) but did not receive CS-alone presentations during extinction training.