Table 1.
Average reference memory errors per trial before and after stimulation/control in the different groups
Group | Week - 2 | Week - 1 | Week 1 | Week 4 | Week 7 |
---|---|---|---|---|---|
Control 10-AD | 0.39 ± 0.14 | 0.1 ± 0.08 | 1.0 ± 0.34 | 0.88 ± 0.29 | 1.61 ± 0.32 |
10-AD | 0.3 ± 0.14 | 0.25 ± 0.1 | 2.28 ± 0.27ab | 1.88 ± 0.26ab | 1.5 ± 0.31 |
Control 5-AD | 0.33 ± 0.1 | 0.4 ± 0.08 | 0.63 ± 0.18 | 0.69 ± 0.26 | |
5-AD | 0.56 ± 0.15 | 0.29 ± 0.09 | 0.63 ± 0.08b | 1.13 ± 0.24b | |
Control LTP | 0.35 ± 0.15 | 0.24 ± 0.11 | 0.68 ± 0.19 | 1.21 ± 0.45 | |
LTP | 0.23 ± 0.06 | 0.19 ± 0.07 | 0.69 ± 0.27 | 0.88 ± 0.23 |
Week - 2 was the average of the eight trials from - 7 to -4 d before stimulation treatment, week - 1 was the average of six trials from - 3 to - 1 d before, and weeks 1, 4, and 7 are averages of four trials during the particular week after treatment. Treatment consisted of control group for 10 ADs, 10-AD group, control for 5 ADs, 5-AD group, control for the primed burst stimulation (PBS) or long-term potentiation group and the LTP group given 12 primed-burst train stimulation. All groups had eight rats except LTP, and its control groups had seven rats. Blank entries indicate data were not available.
P < 0.05, between one experimental group and its control group, post hoc Newman-Keuls test,
P < 0.05, Wilcoxon test, between 10-AD and 5-AD groups.