Table 3.

Normalized dentate gyrus population spike amplitude evoked by medial perforant path in groups given 10 afterdischarges (ADs) or primed-burst stimulation trains (PBS) and their respective control groups

Group	N	1 h post 1st day treatment	1 h post 2nd day treatment	Day 1	Day 4/5	Day 22/23	Day 27/28
Control 10-AD	5	1.07 ± 0.07	1.09 ± 0.12	1.06 ± 0.12	0.94 ± 0.15	1.13 ± 0.22	1.02 ± 0.16
10-ADb	7	0.91 ± 0.22	1.34 ± 0.27	1.48 ± 0.16a	1.5 ± 0.14a	1.43 ± 0.17a	1.47 ± 0.1a
Control LTP	4	1.11 ± 0.14	0.92 ± 0.17	1.0 ± 0.14	1.19 ± 0.11	0.86 ± 0.09	0.89 ± 0.21
LTP	5	1.2 ± 0.23	1.25 ± 0.17	1.5 ± 0.14ac	1.3 ± 0.07a	0.77 ± 0.19d	0.83 ± 0.21d

The average population spike amplitude during the 5 d immediately before stimulation treatment was used for normalization. The first and second columns are data recorded 1 h after the last AD or control treatment of the first day and second day, respectively. Rightmost four columns are data after treatment. 10-AD control and experimental rats were recorded on days 5, 23, and 27 after treatment, while long-term potentiation (LTP) rats and their controls were recorded on days 4, 22, and 28 after 12 primed burst stimulation trains or control.

^aSignificantly different (P < 0.05) from baseline before treatment (Wilcoxon).

^bSignificantly different (P < 0.05) from its own control group (main effect, ANOVA).

^cSignificantly different (P < 0.05) from its own control group, post hoc Newman-Keuls test after significant interaction in ANOVA.

^dLTP group significantly different (P < 0.05) from 10-AD group, post hoc Newman-Keuls test after significant interaction in ANOVA.