Table 4.
Normalized magnitude of polysynaptic apical wave in CA1 evoked by medial perforant path in groups given 10 afterdischarges (ADs) or 12 primed-burst stimulation trains (long-term potentiation or LTP group) and their respective control group
| Group | N | 1 h post 1st day treatment | 1 h post 2nd day treatment | Day 1 | Day 4/5 | Day 22/23 | Day 27/28 |
|---|---|---|---|---|---|---|---|
| Control 10-AD | 5 | 1.15 ± 0.11 | 1.18 ± 0.09 | 1.17 ± 0.13 | 1.11 ± 0.09 | 1.0 ± 0.04 | 1.04 ± 0.08 |
| 10-AD | 7 | 1.11 ± 0.14 | 1.14 ± 0.14 | 1.37 ± 0.11a | 1.18 ± 0.08 | 1.19 ± 0.11 | 1.06 ± 0.06 |
| Control LTP | 4 | 0.84 ± 0.08 | 0.88 ± 0.04 | 0.79 ± 0.08 | 0.84 ± 0.12 | 0.91 ± 0.19 | 0.83 ± 0.31 |
| LTPb | 5 | 1.06 ± 0.07 | 0.9 ± 0.09 | 0.99 ± 0.08 | 0.93 ± 0.07 | 0.89 ± 0.11 | 0.96 ± 0.11 |
Columns as explained in Table 3.
a
Significantly different (P < 0.05) from baseline before treatment, Wilcoxon.
b
LTP group significantly different (P < 0.05) from 10-AD group, main effect, repeated measures ANOVA.