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. 2026 Sep 10;7:1809697. doi: 10.3389/fragi.2026.1809697

TABLE 2.

Baseline biochemical characteristics and intake of participants according groups.

Parameters All CG LMP P-values
181 93 88
HbA1c (%) 5.9 ± 0.2 5.9 ± 0.2 5.9 ± 0.2 0.29
Glucose (mmol/L) 5.9 ± 1.6 6.1 ± 1.6 5.7 ± 1.5 0.11
WBC (103/µL) 7.3 ± 1.9 7.2 ± 1.7 7.4 ± 2.0 0.43
Lymphocytes (%) 38.0 ± 8.5 38.8 ± 9.2 37.1 ± 7.5 0.17
MCV (fL) 84.5 ± 6.1 84.0 ± 6.6 85.0 ± 5.5 0.29
RCD width (%) 13.5 ± 1.6 13.5 ± 1.5 13.4 ± 1.6 0.59
Albumin (g/dL) 3.8 ± 0.5 3.9 ± 0.5 3.8 ± 0.5 0.21
Crea (mg/dL) 0.9 ± 0.2 0.9 ± 0.2 0.9 ± 0.3 0.16
ALP (U/L) 79.5 ± 28.4 78.4 ± 21.1 80.7 ± 34.6 0.60
CRP (mg/L) 2.5 (2.5–6.2) 2.5 (2.5–6.8) 2.5 (2.5–5.7) 0.59
GDF15 (pg/mL) 788.0 (530–1203) 750.0 (578–1134) 789.2 (466–1222) 0.80
SOST (pg/mL) 162.3 (78.5–237.8) 135.7 (77.4–214.1) 185.6 (80.2–252.4) 0.62
Intake (Kcal) 2048.6 (1830–2239) 2110.1 (1908–2289) 1984.1 (1765–2203) 0.14

Data presented as Mean ± SD, for normal parameters; N (%) is used to present categorical variables. Significance set at p < 0.05. No covariate adjustment was performed as groups were balanced at baseline on all measured parameters. Abbreviations: SD, standard deviation; Q1, Quartile 1; Q3, Quartile 3; HbA1c, Hemoglobin A1c; WBC, white blood cell count; MCV, mean corpuscular volume; RCD, width, Red Cell Distribution Width; ALP, alkaline phosphatase; CRP, C-Reactive Protein; GDF15, Growth Differentiation Factor 15; SOST, sclerostin.