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. Author manuscript; available in PMC: 2006 Feb 3.
Published in final edited form as: Alcohol Clin Exp Res. 2005 Jun;29(6):949–957. doi: 10.1097/01.ALC.0000167740.19702.8C

Fig. 4.

Fig. 4

Consumption of 20% ethanol (A) and food intake (B) expressed as g/kg/8 hr by C57BL/6J mice after ICV infusion of the MCR antagonist AgRP-(83-132) (0.05 or 0.1 μg) or aCSF. Plasma ethanol levels 2 and 4 hr after ip injection of 4.0 g ethanol/kg (C). Ten minutes before ethanol injection, mice were given ICV infusion of AgRP-(83-132) (0.05 μg) or aCSF. All values are means ± SEM. ANOVAs indicated that the 0.05-μg dose of AgRP-(83-132) significantly increased ethanol drinking but did not alter food intake. Furthermore, pretreatment with AgRP-(83-132) did not influence plasma ethanol levels

*p < 0.05 relative to aCSF infusion.