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. 2006 Feb 2;34(2):697–708. doi: 10.1093/nar/gkj470

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© The Author 2006. Published by Oxford University Press. All rights reserved

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Non-Watson–Crick base pairs in crystal structures of studied SRD motifs. Tetraloop region, (a) trans SE/H G/A base pair; G-bulged region, (b) G/U/A triplet of cis SE/H G/U and trans WC/H U/A base pairs; flexible region, (c) trans H water-mediated A/C base pair; (d) trans SE/H water-mediated U/C base pair, (e) trans H A/A base pair and (f) trans SE/H C/C base pair. (a–d) are based on the crystal structure of ECOLI system (PDB, 1Q9A), (e and f) are based on the crystal structure of mutated RAT system (PDB, 1Q96). (g) Stereo view of the flexible region of the RAT crystal structure (PDB, 430D) with unpaired bases in A/A and C/C base pairs (highlighted).