FIG. 4.

Inhibition of parasite growth by antibodies (α) directed towards different regions of MSP-1 (p83, p30, p38, and p42). Rabbit sera specific for the four processing fragments were diluted to give suboptimal inhibition of parasite growth before the indicated combinations were composed and assayed for growth inhibition by the LDH assay. Antibodies were added to the assay mixtures in a volume of 40 μl containing 10 μl of each serum, as indicated, and whenever necessary adjusted to 40 μl with medium. Light columns, inhibition calculated from the expected contribution of the individual antibody preparations; dark columns, inhibition measured. Error bars show standard deviations.