FIG. 7.

Inhibition of parasite multiplication by human anti-p83 antibodies. Antibodies specific for p83 were isolated via antigen affinity chromatography from serum of a semi-immune blood donor from Nouna, Burkina Faso. (A) Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (12% polyacrylamide) followed by Western blot analysis of serum (top) and of purified anti-p83 antibodies (bottom). Serum and antibodies were probed against recombinant p83, p30, p38, p42, MSP-7, and MSP-6. MW, molecular weight (in thousands). (B) Inhibition of parasite replication by anti-p83 (αp83) antibodies at the concentrations indicated (measured by the LDH assay); human IgG served as a control. Error bars show standard deviations.