FIG. 2.

Production of IFN-γ by purified NK cells from C57BL/6 mice in response to C. albicans in the presence of cytokines. NK cells were cultured without (control) or with the indicated stimuli (75 or 150 μg [dry weight] of heat-killed C. albicans cells per ml [samples 1 and 2, respectively]) in the presence of IL-2 (A), IL-12 (B), or IL-15 (C). IFN-γ was quantified in the 48-h supernatants by ELISA. The results depicted are mean values (± SD) of duplicates from one representative assay of three. * and **, P < 0.05 and P < 0.01, respectively, compared to either the control or zymosan-treated sample.