TABLE 3.
Risk of reinfection in children with E. histolytica infectionsa
| No. of previous infections | Person-time (days)b | No. of infections | Incidencec | Adjusted relative hazard | 95% CI | P value |
|---|---|---|---|---|---|---|
| 0 | 154,946 | 180 | 0.12 | |||
| 1 | 99,342 | 100 | 0.10 | 0.97 | 0.76, 1.25 | 0.85 |
| 2 | 43,095 | 50 | 0.12 | 1.15 | 0.80, 1.65 | 0.45 |
| 3 | 14,681 | 19 | 0.13 | 1.28 | 0.74, 2.22 | 0.37 |
| ≥4 | 10,985 | 29 | 0.26 | 2.54 | 1.69, 3.81 | <0.0001 |
a
The incidence of Entamoeba histolytica infection and reinfection and the adjusted hazard ratio for repeat infections were calculated using the Andersen-Gill proportional hazards method adjusted for age in months, gender, baseline serum anti-E. histolytica IgG, and area of residence within Mirpur. Siblings (n = 36) were excluded from this analysis.
b
No. of total days of observation contributed by cohort study population.
c
No. of infections per 100 child-days.