TABLE 4.
Incidence of Entamoeba histolytica reinfection in children with and without prior stool anti-CRD IgAa
No. of previous infections | Previous stool anti-CRD IgA | Person-time (days) | No. of infections | Incidenceb | Adjusted relative hazard | 95% CI | P value |
---|---|---|---|---|---|---|---|
1 | Negative | 26,192 | 53 | 0.20 | |||
1 | Positive | 73,150 | 47 | 0.06 | 0.28 | 0.18, 0.44 | <0.0001 |
2 | Negative | 17,236 | 32 | 0.18 | 0.85 | 0.53, 1.36 | 0.50 |
2 | Positive | 25,859 | 18 | 0.07 | 0.30 | 0.17, 0.50 | <0.0001 |
≥3 | Negative | 12,465 | 35 | 0.28 | 1.20 | 0.74, 1.95 | 0.45 |
≥3 | Positive | 13,201 | 13 | 0.10 | 0.40 | 0.20, 0.79 | 0.008 |
Incidence of Entamoeba histolytica reinfection and adjusted relative risk for repeat infections were calculated using the Andersen-Gill proportional hazards method adjusted for age in months, gender, baseline serum anti-E. histolytica IgG, and area of residence within Mirpur. Siblings (n = 36) were excluded from this analysis. See Table 3 for definition of person-time.
No. of infections per 100 child-days.