TABLE 5.
Incidence of Entamoeba histolytica diarrheal episodes in children with and without prior stool anti-CRD IgAa
No. of previous diarrheal ep.b | Previous stool anti-CRD IgA | Person-time (days) | No. of diarrheal episodes | Incidencec | Adjusted relative hazard | 95% CI | P value |
---|---|---|---|---|---|---|---|
0 | Negative | 46,214 | 22 | 0.05 | |||
0 | Positive | 242,231 | 17 | 0.007 | 0.16 | 0.08, 0.30 | <0.0001 |
1 | Negative | 6,522 | 12 | 0.18 | 3.66 | 1.62, 8.24 | 0.002 |
1 | Positive | 14,840 | 3 | 0.02 | 0.48 | 0.14, 1.66 | 0.25 |
≥2 | Negative | 5,886 | 17 | 0.29 | 7.07 | 3.50, 14.29 | <0.0001 |
≥2 | Positive | 5,938 | 2 | 0.03 | 0.75 | 0.20, 2.83 | 0.68 |
Incidence of Entamoeba histolytica-associated diarrheal episodes and adjusted relative risk for repeat diarrheal episodes were calculated using the Andersen-Gill proportional hazards method adjusted for age in months, gender, baseline IgG, and area of residence within Mirpur. Siblings (n = 36) were excluded from this analysis. See Table 3 for definition of person-time.
ep., episodes.
No. of diarrheal episodes per 100 child-days.