FIG. 6.

Airway inflammation and systemic immune activation following intranasal SEB challenge in HLA-DQ8 transgenic mice. Age-matched HLA-DQ8 mice were challenged intranasally with either PBS or SEB (2,000 ng) on days 0, 3, and 6. On day 8, BAL fluid was collected for flow cytometric analysis (A to C). FSc, forward scatter. Enumeration of leukocyte subsets by use of Wright-Giemsa-stained cytospin preparations (D). Panel E represents the T-cell subsets in spleens. Each data point represents the mean ± standard error from four mice. *, P < 0.05.