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. 2002 Apr;76(7):3329–3337. doi: 10.1128/JVI.76.7.3329-3337.2002

FIG. 5.

FIG. 5.

Three populations of virus-specific effector T cells. Splenocytes collected from BALB/c mice on day 7 after VV infection were stimulated in vitro with VV-infected A-20 cells and costained intracellularly for either IFN-γ and TNF-α (top panels) or IFN-γ and IL-2 (bottom panels). The data shown are gated on either CD8 or CD4 T cells, and the numbers within the panels represent the frequencies of the CD8 or CD4 T cells producing each cytokine.