TABLE 1.

Cytokine-producing T-cell subset frequencies^a

Cytokine(s) produced	% CD8	% CD4
IFN-γ	59	51
IFN-γ, TNF-α	25	8
IFN-γ, TNF-α, IL-2	16	41

^aThe frequencies of VV-specific CD8 and CD4 T cells producing the indicated cytokine profiles were determined at the peak of the T-cell response (day 7 postinfection) by intracellular cytokine staining.