ADMET	absorption, distribution, metabolism, excretion, and toxicity
AI	artificial intelligence
ATOM	Accelerating Therapeutics for Opportunities in Medicine
CBVLS	compound-based virtual ligand screening
CDISC	Clinical Data Interchange Standards Consortium
CRDC	Cancer Research Data Commons
CTD	Common Technical Document
DL	deep learning
EBI	European Bioinformatics Institute
EHR	electronic health records
EMA	European Medicines Agency
EMBL	European Molecular Biology Laboratory
EU	European Union
FAIR	Findable, Accessible, Interoperable, and Reusable
FDA	Food and Drug Administration
FHIR	Fast Healthcare Interoperability Resources
GDC	Genomic Data Commons
GDPR	General Data Protection Regulation
HCS	high content screening
HIPAA	Health Insurance Portability and Accountability Act
HTS	High-Throughput Screening
ICH	International Council of Harmonisation
InChI	International Chemical Identifier
LLM	large language model
MCTS	Monte Carlo tree search
MIDD	Model-Informed Drug Development
MLPCN	Molecular Library Probe Production Centers Network
ML	machine learning
NCI	National Cancer Institute
NDA	New Drug Application
NIH	National Institutes of Health
OMOP	Observational Medical Outcomes Partnership
PDB	Protein Data Bank
PHI	protected health information
QSAR	quantitative structure–activity relationships
RBVLS	receptor-based virtual ligand screening
RECIST	Response Evaluation Criteria in Solid Tumors
RTOR	Real-Time Oncology Review
RWD	real-world data
RWE	real-world evidence
SMILES	Simplified Molecular Input Line Entry System
TCGA	The Cancer Genome Atlas
US	United States
USD	United States dollar
VA	U.S. Department of Veterans Affairs
VLS	virtual ligand screening