FIG. 7.
Effect of BDM on the yield of infectious virus. Monolayers of Vero cells (106) were infected with HSV-1 strain 17 (MOI of 10), and BDM was added at a range of concentrations at 12 h p.i. At 20 h p.i., medium (circles) or cell-associated virus (triangles) was collected, and the numbers of released was viruses determined by plaque assay. Results are plotted as a percentage of the yields of virus in the absence of drug, which were 1.1 × 105 for released virus and 0.5 × 105 for cell-associated virus.