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. 2006 Jan 19;103(5):1593–1598. doi: 10.1073/pnas.0508901103

Fig. 1.

Fig. 1.

Plasma leptin levels after CUS or chronic social defeat. (A) Effect of CUS for 14 days on plasma leptin levels and corticosterone at 24 h after the cessation of the final stressor or after 30 min of acute restraint stress (AS) on day 15. Control, n = 13; control with acute stress, n = 9; CUS, n = 12; CUS with acute stress, n = 11. ANOVAs indicated significant effects for CUS [F(1,40) = 13.37, P < 0.001 for leptin; F(1,40) = 5.55, P < 0.05 for corticosterone] and acute stress [F(1,40) = 4.923, P < 0.05 for leptin; F(1,40), P < 0.0001 for corticosterone]. *, P < 0.05 compared with controls; ++, P < 0.01 compared with control animals subjected to acute stress. (B) Effect of chronic social defeat (SD) for 10 days on plasma leptin levels at 24 h after the last SD. Control, n = 6; SD, n = 6. Two-tailed t test, P < 0.05.