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. 2026 Sep 17;15(18):1687. doi: 10.3390/cells15181687
2D Two-dimensional
3D Three-dimensional
BC Breast cancer
BSA Bovine serum albumin
CD44t Total CD44 isoform
CEMIP Cell migration-inducing hyaluronidase
DAPI 4′,6-diamidino-2-phenylindole
DMEM Dulbecco’s Modified Eagle Medium
ECM Extracellular matrix
EMT Epithelial-to-mesenchymal transition
GAG Glycosaminoglycan
GlcA D-glucuronic acid
GlcNAc N-acetyl-D-glucosamine
HA Hyaluronan/hyaluronic acid
HAS1/2/3 Hyaluronan synthase 1, 2, 3
HAS2-AS1 HAS2 antisense RNA 1
HMW High-molecular-weight
LMW Low-molecular-weight
MMP Matrix metalloproteinase
MMP-14 Matrix metalloproteinase 14
PBS Phosphate-buffered saline
PFA Paraformaldehyde
PI3K Phosphoinositide 3-kinase
PG Proteoglycan
RHAMM Receptor for hyaluronan-mediated motility
SEM Scanning electron microscopy
sHA Sulfated hyaluronan
SNAI2 Snail family transcriptional repressor 2 (Slug)
TMEM2 Transmembrane protein 2 (hyaluronidase)
TME Tumor microenvironment
TNBC Triple-negative breast cancer
TPM Transcripts per million