FIG. 3.

Infection with parental VZV and the ORF2 deletion mutant results in similar VZV DNA copy numbers in dorsal root ganglia. Copy number was estimated by densitometry. The VZV genome copy numbers for animals that were considered positive for VZV (filled circles) and for animals that had genome copy numbers below the threshold for reliable detection of DNA (<10 copies of VZV DNA per 500 ng of ganglia DNA) (open circles) are shown. The geometric mean copy numbers of VZV genomes per 500 ng of ganglia DNA in PCR-positive animals are shown below the graphs.