Table 2. Number of sites compared, rate difference between human and chimpanzee, and the ratio of chimpanzee-specific versus human-specific substitutions from data set 2.
| Introns
|
Intergenic regions
|
|||||
|---|---|---|---|---|---|---|
| Chromosome | Number of sites compared | d = Kbh – Kbc (per 10 kb) | KOC/KOH | Number of sites compared | d = Kbh – Kbc (per 10 kb) | KOC/KOH |
| 2 | 41,571 (25,457) | –8.639 ± 5.864 (–9.751 ± 7.238) | 1.146 (1.177) | 143,774 (112,336) | 2.911 ± 2.918 (1.900 ± 3.157) | 0.949 (0.963) |
| 4 | 36,539 (18,257) | –3.040 ± 6.383 (–1.209 ± 8.457) | 1.048 (1.021) | 55,184 (19,556) | –7.973 ± 6.202 (–6.889 ± 10.292) | 1.093 (1.081) |
| 8 | 25,135 (17,869) | –14.124 ± 7.646 (–24.117 ± 8.961)** | 1.251 (1.482) | 55,151 (32,783) | 1.207 ± 6.206 (–0.671 ± 7.897) | 0.987 (1.007) |
| 10 | 33,533 (26,022) | –1.6288 ± 6.633 (–1.680 ± 7.542) | 1.025 (1.026) | 91,889 (45,965) | –6.388 ± 4.082 (–2.123 ± 5.719) | 1.099 (1.032) |
| 12 | 49,266 (46,909) | –12.497 ± 4.452** (–12.434 ± 4.581)** | 1.323 (1.318) | 113,283 (91,873) | –13.55 ± 3.127** (–16.419 ± 3.387)** | 1.314 (1.414) |
| 16 | 136,363 (68,749) | –7.487 ± 3.495* (–10.113 ± 4.438)* | 1.108 (1.183) | 48,813 (16,310) | –16.701 ± 6.070** (–3.345 ± 9.107) | 1.244 (1.058) |
| 18 | 145,283 (121,412) | –2.141 ± 2.819 (–5.097 ± 2.964) | 1.041 (1.110) | – | – | – |
| 21 | 132,603 (74,660) | –9.888 ± 3.826** (0.597 ± 5.201) | 1.125 (0.993) | 41,290 (25,445) | –25.768 ± 7.379** (–36.296 ± 9.799)** | 1.306 (1.418) |
| 22 | 443,452 (264,488) | –15.681 ± 1.780** (–15.797 ± 2.190)** | 1.292 (1.327) | 214,581 (116,725) | –6.156 ± 2.711* (–1.983 ± 3.583) | 1.095 (1.031) |
| Total | 1,043,745 (663,823) | –10.607 ± 1.181** (–10.222 ± 1.408)** | 1.180 (1.191) | 763,965 (460,993) | –6.873 ± 1.427** (5.961 ± 1.755)** | 1.106 (1.099) |
Intergenic regions from the chromosome 18 are shorter than 250 bp and not included in this analysis. Notations are the same as in Table 1. *, P < 0.05; **, P < 0.01 by the relative rate test.