Figure 3.

Peritoneal macrophages isolated from male LDL-R null mice contain more CD36 than female mice treated with ritonavir. LDL-R null mice were treated with vehicle (0.01% ethanol) or ritonavir (10μg/day) for 8 weeks. Peritoneal macrophages were isolated and processed for immunoblots. Total cell lysates were generated and 20 μg of protein was resolved by SDS-PAGE and immunobloted with antibodies for CD36 and SR-A. Reactive material was visualized by chemiluminescence (Figure 3A). Relative densities were quantified and represented as fold increase over vehicle control (Figure 3B). Bars represent mean +/- SEM, n = 4, * = significantly different from vehicle, p<0.05.