TABLE 3.
Quantitation of cells of lymphoid organs of control and CD4C/SHIV-nefSIV Tg mice
| Mice | Cells (106)a in:
|
||
|---|---|---|---|
| Thymus | Spleen | Mesenteric LN | |
| Non-Tg (n = 19) | 118 ± 67.5 | 43.7 ± 17.2 | 9.4 ± 2.0 |
| Tg F55541 (n = 10) | 5.99 ± 2.9*** | 146.0 ± 5.7* | 9.5 ± 5.7 |
| Tg F57693 (n = 6) | 12.2 ± 6.8** | 80 ± 17 | 6.8 ± 2.0 |
| Tg F27367 (n = 7) | 117 ± 47.9 | ND | ND |
a
Data for thymuses were obtained on 21-day-old animals. Data for spleens and mesenteric LN were obtained on 3- to 16-week-old animals. ND, not done. P values by Student's t test: *, P ≤ 0.05; **, P < 0.001; ***, P < 0.0001.