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. Author manuscript; available in PMC: 2007 Jan 1.
Published in final edited form as: Cancer Res. 2006 Jan 1;66(1):259–266. doi: 10.1158/0008-5472.CAN-05-2502

Figure 1.

Figure 1

Host MMP contributions to lung tumor formation. (A) Number of surface lung tumors in control (n=12) and MMP2 null (n=12) mice 2 weeks after injection of 3 x 105 LLC cells i.v. (p=NS). (B) Tumor size in control and MMP2 null mice (p=NS). (C) Number of surface lung tumors in control (n=14) and MMP7 null (n=14) mice 2 weeks after injection of 3 x 105 LLC cells i.v. (*p=0.01). (D) Tumor size in control and MMP7 null mice (p=NS). (E) Number of surface lung tumors in control (n=13) and MMP9 null (n=11) mice 2 weeks after injection of 3 x 105 LLC cells i.v. (*p=0.0002). (F) Tumor size in control and MMP9 null mice (p=NS).