Table 1. HA inhibitory activity of gp-340 preparations.
Amount required for inhibition (ng/ml) | ||||
---|---|---|---|---|
Salivary gp-340 | ||||
Viral strain | Sialic acid binding preference | Lung gp-340 | Donor 1 | Donor 2 |
Phil82 | α(2,6)-Linkage | 312±43 | 291±69 | 268±38 |
Braz79 | α(2,6)-Linkage | 341±77 | 347±75 | ND |
PR-8 | α(2,3)-Linkage | 275±25 | 74±3* | 204±51 |
Sendai | α(2,3)-Linkage | ND | 126±8* | 245±10 |
Phil82/BS | α(2,6) and α(2,3)-Linkage | 210±37 | 84±12* | ND |