| ABAD | Amyloid-binding alcohol dehydrogenase |
| ACSL4 | Acyl-CoA synthetase long-chain family member 4 |
| AD | Alzheimer’s disease |
| AHEAD 3–45 | Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (clinical trial) |
| ANLS | Astrocyte-Neuron Lactate Shuttle |
| APOE | Apolipoprotein E |
| APOE4 | Apolipoprotein E ε4 allele/gene |
| APP | Amyloid precursor protein |
| ARE | Antioxidant response element |
| ATP | Adenosine triphosphate |
| ATP7A/ATP7B | Copper-transporting P-type ATPases A/B |
| Aβ | Amyloid-beta |
| BACE1 | Beta-site Amyloid Precursor Protein Cleaving Enzyme 1 |
| CDK5 | Cyclin-dependent kinase 5 |
| CoQ10 | Coenzyme Q10 |
| CTR1 | Copper transporter 1 |
| CSF | Cerebrospinal fluid |
| DAM | Disease-associated microglia |
| DAMPs | Damage-associated molecular patterns |
| DHODH | Dihydroorotate dehydrogenase |
| DMT1 | Divalent metal transporter 1 |
| ELAD | ‘Evaluating Liraglutide in Alzheimer’s Disease’ (clinical trial) |
| EVOKE/EVOKE+ | Phase 3 clinical trials of oral semaglutide in early symptomatic Alzheimer’s disease |
| FDG-PET | Fluorodeoxyglucose positron emission tomography |
| FSP1 | Ferroptosis suppressor protein 1 |
| GLP-1 | Glucagon-like peptide-1 |
| GLUT1 | Glucose transporter 1 |
| GLUT3 | Glucose transporter 3 |
| GPX4 | Glutathione peroxidase 4 |
| GSDMD | Gasdermin D |
| GSH | Glutathione |
| GSK3β | Glycogen synthase kinase-3β |
| HDAC(s) | Histone deacetylase(s) |
| HETEs | Hydroxyeicosatetraenoic acids |
| IL-18 | Interleukin-18 |
| IL-1β | Interleukin-1β |
| KEAP1 | Kelch-like ECH-associated protein 1 |
| LIP | Labile iron pool |
| LPCAT3 | Lysophosphatidylcholine acyltransferase 3 |
| LPS | Lipopolysaccharide |
| LTP | Long-term potentiation |
| MCT1/2/4 | Monocarboxylate transporter 1/2/4 |
| MLKL | Mixed lineage kinase domain-like protein |
| NAD+ | Nicotinamide adenine dinucleotide (oxidised form) |
| NADPH | Nicotinamide adenine dinucleotide phosphate (reduced form) |
| NCOA4 | Nuclear receptor coactivator 4 |
| NLRP3 | NOD-, LRR- and pyrin domain-containing protein 3 |
| NMDA | N-methyl-D-aspartate |
| NO | Nitric oxide |
| NRF2 | Nuclear factor erythroid 2-related factor 2 |
| oxPEs | Oxidised phosphatidylethanolamines |
| OXPHOS | Oxidative phosphorylation |
| oxPUFAs | Oxidised polyunsaturated fatty acids |
| p-tau217 | Phosphorylated tau at threonine 217 (blood biomarker) |
| PANoptosis | Combined apoptosis, pyroptosis, and necroptosis cell death pathway |
| PI3K/Akt | Phosphoinositide 3-kinase/protein kinase B signalling pathway |
| QSM | Quantitative susceptibility mapping |
| RCD | Regulated cell death |
| RIPK1/3 | Receptor-interacting protein kinase 1/3 |
| RNS | Reactive nitrogen species |
| ROS | Reactive oxygen species |
| SCFAs | Short-chain fatty acids |
| SS-31 | Elamipretide (mitochondria-targeted, cardiolipin-stabilising peptide) |
| TCA | Tricarboxylic acid |
| TfR1 | Transferrin receptor 1 |
| TLR4 | Toll-like receptor 4 |
| TNF-α | Tumour necrosis factor-α |
| TPP+ | Triphenylphosphonium cation |
| ZIP | Zrt/Irt-like protein (zinc transporter, SLC39 family) |
| ZnT | Zinc transporter (SLC30 family) |
| β-HB | Beta-hydroxybutyrate |