53BP1	p53-binding protein 1
Akt	Protein kinase B
AML	Acute myeloid leukaemia
AMPK	AMP-activated protein kinase
alt-EJ	Alternative end joining
ATM	Ataxia-telangiectasia mutated
ATR	Ataxia-telangiectasia and Rad3-related protein
AURKA	Aurora kinase A
AURKB	Aurora kinase B
BARD1	BRCA1-associated RING domain protein 1
BER	Base excision repair
BRCA	Breast cancer susceptibility gene/protein
CAK	CDK-activating kinase
CDK	Cyclin-dependent kinase
CHK1	Checkpoint kinase 1
CIN	Chromosomal instability
DDR	DNA damage response
DNA-PK	DNA-dependent protein kinase
DSB	DNA double-strand break
DYRK1A	Dual-specificity tyrosine-phosphorylation-regulated kinase 1A
DYRK1B	Dual-specificity tyrosine-phosphorylation-regulated kinase 1B
E3	E3 ubiquitin ligase
eIF2α	Eukaryotic translation initiation factor 2 alpha
EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3; gene name for PERK
FANCA	Fanconi anaemia complementation group A
FHIT	Fragile histidine triad protein
FOXO3a	Forkhead box O3
Fyn	Fyn-related Src family tyrosine kinase
G2	Gap 2 phase of the cell cycle
G2/M	Gap 2/mitosis transition
GSK3β	Glycogen synthase kinase 3 beta
H2AX	H2A histone family member X
γH2AX	Phosphorylated H2AX
HR	Homologous recombination
HRD	Homologous recombination deficiency
ISR	Integrated stress response
KRAS	Kirsten rat sarcoma virus oncogene homologue
Lck	Lymphocyte-specific protein tyrosine kinase
MAPK	Mitogen-activated protein kinase
MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2
MCL-1	Myeloid cell leukaemia 1
MK2	MAP kinase-activated protein kinase 2
MPS1	Monopolar spindle 1 kinase
mTOR	Mechanistic target of rapamycin
MRE11	Double-strand break repair protein meiotic recombination 11
Myc	Myc proto-oncogene/transcription factor
NEK2	NIMA-related kinase 2
NER	Nucleotide excision repair
NHEJ	Non-homologous end joining
NIMA	Never in mitosis A
NRF2	Nuclear factor erythroid 2-related factor 2
PALB2	Partner and localiser of BRCA2
PARP	Poly(ADP-ribose) polymerase
PARPi	PARP inhibitor
PDHK1	Pyruvate dehydrogenase kinase 1
PERK	protein kinase R (PKR)-like endoplasmic reticulum kinase
PI3K	Phosphoinositide 3-kinase
PLK1	Polo-like kinase 1
Pol II	RNA polymerase II
PROTAC	Proteolysis-targeting chimera
p38 MAPK	p38 mitogen-activated protein kinase
p53	Protein product of TP53
p-RPA	Phosphorylated replication protein A
RAD51	Radiation sensitive protein 51/RAD51 recombinase
RAD51B	RAD51 paralog B
RAD51C	RAD51 paralog C
RAD51D	RAD51 paralog D
R-loops	RNA–DNA hybrid structures with displaced single-stranded DNA
ROS	Reactive oxygen species
RPA	Replication protein A
SAC	Spindle assembly checkpoint
SFKs	Src family kinases
SGK1	Serum- and glucocorticoid-regulated kinase 1
Src	SRC proto-oncogene tyrosine-protein kinase
SSA	Single-strand annealing
SSB	DNA single-strand break
STAT	Signal transducer and activator of transcription
TBK1	TANK-binding kinase 1
TFIIH	Transcription factor II H
TP53	Tumour protein p53 gene
TTK/MPS1	TTK protein kinase/monopolar spindle 1 kinase
UPR	Unfolded protein response
WEE1	Wee1 G2 checkpoint kinase
WIP1	Wild-type p53-induced phosphatase 1
XRCC2	X-ray repair cross-complementing protein 2
XRCC3	X-ray repair cross-complementing protein 3