Abbreviation	Definition	Abbreviation	Definition
8-OHdG	8-hydroxy-2′-deoxyguanosine	A20	tumour necrosis factor alpha-induced protein 3 (TNFAIP3)
AAA	abdominal aortic aneurysm	ACSL4	acyl-CoA synthetase long-chain family member 4
AMPK	AMP-activated protein kinase	Ang II	angiotensin II
APJ	apelin receptor	ARE	antioxidant response element
ATP7A/ATP7B	copper-transporting P-type ATPases 7A and 7B	BBB	blood–brain barrier
CaMKII	calcium/calmodulin-dependent protein kinase II	CAT	catalase
CCVDs	cardiovascular and cerebrovascular diseases	cGAS–STING	cyclic GMP–AMP synthase–stimulator of interferon genes
cGMP	cyclic guanosine monophosphate	CTR1	copper transporter 1
Cu-MOF	copper-based metal–organic framework	Cul3	cullin 3
CVD	cardiovascular disease	DFO	deferoxamine
DLAT	dihydrolipoamide S-acetyltransferase	Drp1	dynamin-related protein 1
ECM	extracellular matrix	eNOS	endothelial nitric oxide synthase
FDX1	ferredoxin 1	Fe–S	iron–sulphur
FENDRR	FOXF1 adjacent non-coding developmental regulatory RNA	FTH1	ferritin heavy chain 1
GCLC	glutamate-cysteine ligase catalytic subunit	GPX4	glutathione peroxidase 4
GSH	glutathione	GUCY1A1	guanylate cyclase 1 soluble subunit alpha 1
HIF-1α	hypoxia-inducible factor-1α	HIF-2α	hypoxia-inducible factor-2α
HO-1	haem oxygenase 1	I/R	ischaemia–reperfusion
ICH	intracerebral haemorrhage	IRE	iron-responsive element
IRP	iron regulatory protein	IRI	ischaemia–reperfusion injury
Keap1	Kelch-like ECH-associated protein 1	LDL	low-density lipoprotein
LIAS	lipoyl synthase	LIP	labile iron pool
LOX	lysyl oxidase	LPC	lysophosphatidylcholine
Lp-PLA2	lipoprotein-associated phospholipase A2	MAPK	mitogen-activated protein kinase
MMP	matrix metalloproteinase	MOF	metal–organic framework
MT	metallothionein	NADPH	reduced nicotinamide adenine dinucleotide phosphate
NCOA4	nuclear receptor coactivator 4	NF-κB	nuclear factor kappa B
NLRP3	NLR family pyrin domain-containing 3	NO	nitric oxide
NQO1	NAD(P)H quinone dehydrogenase 1	Nrf2	nuclear factor erythroid 2-related factor 2
OXPHOS	oxidative phosphorylation	ox-LDL	oxidised low-density lipoprotein
PB	Prussian blue	PKG	cGMP-dependent protein kinase
PKM2	pyruvate kinase M2	PUFA	polyunsaturated fatty acid
ROS	reactive oxygen species	SENP2	small ubiquitin-like modifier-specific protease 2
SLC7A11	solute carrier family 7 member 11	SMLC	S-methyl-L-cysteine
SOD	superoxide dismutase	SrHCF	strontium-substituted hexacyanoferrate
SSP	serine synthesis pathway	SUMO	small ubiquitin-like modifier
TCA	tricarboxylic acid	TfR1	transferrin receptor 1
TM	tetrathiomolybdate	TNF-α	tumour necrosis factor-α
TNFAIP3	tumour necrosis factor alpha-induced protein 3	UTR	untranslated region
VDAC1	voltage-dependent anion channel 1	VEGF	vascular endothelial growth factor
VEGFR2	vascular endothelial growth factor receptor 2	VSMC	vascular smooth muscle cell
YTHDF2	YTH N6-methyladenosine RNA-binding protein 2	ZIP	Zrt- and Irt-like protein family
ZnT	zinc transporter family