| ADAMTS5 | A disintegrin and metalloproteinase with thrombospondin motifs 5 |
| AF | Annulus fibrosus |
| AKT | Protein kinase B |
| AMPK | AMP-activated protein kinase |
| ANOVA | Analysis of variance |
| ARRIVE | Animal Research: Reporting of In Vivo Experiments |
| BAX | BCL2-associated X protein |
| BCA | Bicinchoninic acid |
| BCL-2 | B-cell lymphoma 2 |
| BSA | Bovine serum albumin |
| CCK-8 | Cell Counting Kit-8 |
| COL2 | Type II collagen |
| DAB | 3,3′-Diaminobenzidine |
| DAPI | 4′,6-Diamidino-2-phenylindole |
| DHI | Disc height index |
| DMEM/F12 | Dulbecco’s Modified Eagle Medium/Nutrient Mixture F-12 |
| DMSO | Dimethyl sulfoxide |
| ECM | Extracellular matrix |
| ECL | Enhanced chemiluminescence |
| EDTA | Ethylenediaminetetraacetic acid |
| FBS | Fetal bovine serum |
| FITC | Fluorescein isothiocyanate |
| Gin-Rh2 | Ginsenoside Rh2 |
| GO | Gene Ontology |
| H&E | Hematoxylin and eosin |
| HRP | Horseradish peroxidase |
| IL-1β | Interleukin-1 beta |
| IVDD | Intervertebral disc degeneration |
| micro-CT | Micro-computed tomography |
| MMP3 | Matrix metalloproteinase 3 |
| MRI | Magnetic resonance imaging |
| NP | Nucleus pulposus |
| NPC | Nucleus pulposus cell |
| PBS | Phosphate-buffered saline |
| PI | Propidium iodide |
| PI3K | Phosphoinositide 3-kinase |
| PIP3 | Phosphatidylinositol 3,4,5-trisphosphate |
| PKA | Protein kinase A |
| PMSF | Phenylmethylsulfonyl fluoride |
| PPI | Protein–protein interaction |
| PVDF | Polyvinylidene difluoride |
| RIPA | Radioimmunoprecipitation assay |
| ROS | Reactive oxygen species |
| SD | Standard deviation |
| SDS-PAGE | Sodium dodecyl sulfate–polyacrylamide gel electrophoresis |
| SO/FG | Safranin O/Fast Green |
| TBST | Tris-buffered saline containing Tween-20 |
| TCM | Traditional Chinese medicine |
| TUNEL | Terminal deoxynucleotidyl transferase dUTP nick-end labeling |