5hmC	5-Hydroxymethylcytosine
5mC	5-Methylcytosine
ABF-1	Activated B-cell factor 1
AICE	AP-1-IRF composite element
AP-1	Activator protein 1
BCR	B-cell receptor
bHLH	Basic helix–loop–helix
CAF	Cancer-associated fibroblast
CE	Composite element
cHL	Classical Hodgkin lymphoma
ChIP	Chromatin immunoprecipitation
ChIP-chip	Chromatin immunoprecipitation coupled to promoter microarrays
CIITA	Class II major histocompatibility complex transactivator
CR	Complete remission
ctDNA	Circulating tumor DNA
DNMT	DNA methyltransferase
EBV	Epstein–Barr virus
EV	Extracellular vesicle
FDC	Follicular dendritic cell
GC	Germinal center
HDAC	Histone deacetylase
HLH	Helix–loop–helix
HLA	Human leukocyte antigen
HRS	Hodgkin and Reed–Sternberg
Ig	Immunoglobulin
IgH	Immunoglobulin heavy chain
IgL	Immunoglobulin light chain
IgVH	Immunoglobulin variable heavy-chain
lncRNA	Long non-coding RNA
LMP1	Latent membrane protein 1
LMP2A	Latent membrane protein 2A
MAPK/ERK	Mitogen-activated protein kinase/extracellular signal-regulated kinase
MGZL	Mediastinal gray zone lymphoma
MHC	Major histocompatibility complex
miRNA	MicroRNA
NF-κB	Nuclear factor kappa B
NGS	Next-generation sequencing
NK	Natural killer
NS-cHL	Nodular sclerosis classical Hodgkin lymphoma
OS	Overall survival
PD-1	Programmed cell death protein 1
PD-L1	Programmed death ligand 1
PD-L2	Programmed death ligand 2
PFS	Progression-free survival
PMBCL	Primary mediastinal large B-cell lymphoma
PRC1	Polycomb repressive complex 1
PRC2	Polycomb repressive complex 2
RS	Reed–Sternberg
siRNA	Small interfering RNA
TAM	Tumor-associated macrophage
TARC	Thymus and activation-regulated chemokine
TCR	T-cell receptor
TET	Ten-eleven translocation
Tfh	Follicular T helper
TMA	Tissue microarray
TME	Tumor microenvironment
Treg	Regulatory T cell
TSA	Trichostatin A