JMML	Juvenile myelomonocytic leukemia
RTK	Receptor tyrosine kinases
HSPCs	Haematopoietic stem/progenitor cells
MDS	Myelodysplastic syndromes
WHO	World Health Organization
ICC	International Consensus Classification
HSCT	Hematopoietic stem cell transplantation
WES	Whole-exome sequencing
BM	Bone marrow
SNVs	Single nucleotide variants
GATK	Genome Analysis Toolkit
BWA	Burrows–Wheeler Aligner
SNV	Single nucleotide variants
MAF	Mutation Annotation Format
KEGG	Kyoto Encyclopedia of Genes and Genomes
VAF	Variant allele frequencies
FDR	False discovery rate
NMF	Negative matrix factorization
SBS	Single-base substitution