1D	One-Dimensional
2D	Two-Dimensional
4-HPAA	4-Hydroxyphenylacetate
Ace	Acetone
ACEi	Angiotensin-Converting Enzyme inhibitors
ACE-R	Revised Addenbrooke’s Cognitive Test
AChE	Acetylcholinesterase
AnCoa	Anticoagulants
ARA	Angiotensin II Receptor Antagonists
AUC	Area Under the Curve
AUROC	Area Under the Receiver Operating Characteristic Curve
BAA	Beta-Adrenergic Antagonists
BMI	Body Mass Index
BP	Blood Pressure
CCB	Calcium Channel Blockers
Cit	Citrate
CST	Chi-Squared Test
CVMD	Cardiovascular or Metabolic Diseases
DBP	Diastolic Blood Pressure
DIU	Diuretics
DPP-4	Dipeptidyl peptidase-4
EBIcohort	Elders from Beira Interior cohort
FET	Fisher’s Exact Test
GDS	Global Deterioration Scale
HDL cholesterol	High-Density Lipoprotein cholesterol
HT	Hypertension
HTall	Group consisting of participants diagnosed with hypertension (with and without comorbidities)
HTo	Subgroup (inside HTall group) of participants diagnosed with hypertension, without any cardiovascular or metabolic comorbidities.
HTdl	Subgroup of participants diagnosed with hypertension + dyslipidemia, without other cardiovascular or metabolic comorbidities (namely, diabetes or cardiovascular diseases)
HTdb	Subgroup of participants diagnosed with hypertension + diabetes, without other cardiovascular or metabolic comorbidities (namely, dyslipidemia or cardiovascular diseases)
HTcd	Subgroup of participants diagnosed with hypertension + one cardiovascular disease (heart failure, arrhythmia, or history of acute myocardial infarction), without other cardiovascular or metabolic comorbidities (namely dyslipidemia or diabetes)
HTdb•dl	Subgroup of participants diagnosed with hypertension + dyslipidemia + diabetes, without other cardiovascular or metabolic comorbidities (namely, cardiovascular diseases)
HTcd•dl	Subgroup of participants diagnosed with hypertension + dyslipidemia + one cardiovascular disease (heart failure, arrhythmia, or history of acute myocardial infarction), without other cardiovascular or metabolic comorbidities (namely, diabetes)
HTcd•db	Subgroup of participants diagnosed with hypertension + diabetes + one cardiovascular disease (heart failure, arrhythmia, or history of acute myocardial infarction), without other cardiovascular or metabolic comorbidities (namely, dyslipidemia)
JRES	J-RESolved spectroscopy
KWT	Kruskal–Wallis test
LDL cholesterol	Low-Density Lipoprotein cholesterol
LTCF	Long-Term Care Facilities
MAO	Monoamine oxidase
MG	Methylglutaconate
MMSE	Mini-Mental State Examination
MWT	Mann–Whitney Test
N-IVG	N-Isovaleroylglycine
NMDA	N-Methyl-D-Aspartate
NMR	Nuclear Magnetic Resonance
NOESY	Nuclear Overhauser Effect Spectroscopy
NT	Normotensive
OWAT	One-way ANOVA test
Oxa	Oxaloacetate
Phe	Phenylalanine
Pyr	Pyridoxate
S.E.	Standard Error
Sar	Sarcosine
SBP	Systolic Blood Pressure
STT	Student t-test
TOCSY	Total Correlation Spectroscopy
WHO	World Health Organization