Fig. 1.

A 53-y-old male patient with cT4N2bM0 right pyriform sinus cancer (A). The CT scan revealed that the tumor penetrated the thyrohyoid membrane and invaded the strap muscle (B). Following two cycles of ICT, significant tumor shrinkage was observed, nearly achieving complete response (C). The residual tumor was excised using TLM (D). The specimen was sent for pathological examination via en bloc resection (E). The patient underwent adjuvant CRT and remained free of disease for over 4 y (F). CT, computed tomography; ICT = induction chemotherapy; TLM = transoral laser microsurgery.