Table 3.
Tumor stage shift, adjuvant therapy, and treatment outcomes after surgery
| Patient | cT | cN | Clinical stage | ND | N+ max. size (mm) | ENE | pT | pN | Pathological stage | Down stage | PORT/POCCRT | RT dose | Recurrence | Laryngeal preservation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T2 | N2c | IVA | Yes | 25 | Yes | T2 | N3b | IVB | No | Yes | 6600 | No | Yes |
| 2 | T4a | N3b | IVB | Yes | 42 | Yes | T3 | N3b | IVB | No | Yes | 5940 | No | Yes |
| 3 | T3 | N0 | III | No | - | - | T1 | - | I | Yes | No | - | Local | Yes |
| 4 | T2 | N1 | III | Yes | 10 | No | T2 | N0 | II | Yes | Yes | 6400 | No | Yes |
| 5 | T3 | N1 | III | Yes | 28 | Yes | T3 | N2a | IVA | No | Yes | 6600 | Local | No |
| 6 | T4a | N2b | IVA | Yes | 3 | No | T1 | N1 | III | Yes | Yes | 6600 | No | Yes |
| 7 | T3 | N3b | IVB | Yes | 5 | No | T0 | N1 | III | Yes | Yes | 5400 | No | Yes |
| 8 | T4a | N2b | IVA | Yes | 12 | No | Tis | N1 | III | Yes | No | - | Distant | Yes |
| 9 | T2 | N2b | IVA | Yes | 8 | No | T1 | N1 | III | Yes | No | - | No | Yes |
| 10 | T3 | N2c | IVA | Yes | 2 | No | T0 | N2c | IVA | No | Yes | 6000 | No | Yes |
| 11 | T3 | N0 | III | Yes | - | No | T1 | N0 | I | Yes | No | - | No | Yes |
cT = clinical tumor; cN = clinical neck; ENE = extranodal extension; max. = maximal; N+ = neck metastasis; ND = neck dissection; pN = pathological neck; POCCRT = postoperative concurrent chemoradiotherapy; PORT = postoperative radiotherapy; pT = pathological tumor; RT = radiotherapy; “-“ = not applicable.