| AI | artificial intelligence |
| AUC | area under the concentration–time curve |
| CC-3 | cleaved caspase-3 |
| CL | clearance |
| CLint | intrinsic clearance |
| ClpP | caseinolytic protease P |
| Cmax | maximum concentration |
| CYP | cytochrome P450 |
| CYP3A4 | cytochrome P450 3A4 |
| Emax | maximum effect |
| IC50 | half-maximal inhibitory concentration |
| IVIVE | in vitro–in vivo extrapolation |
| IVIVT | in vitro–in vivo translation |
| Ka | absorption rate constant |
| LC–MS/MS | liquid chromatography–tandem mass spectrometry |
| MALDI | matrix-assisted laser desorption/ionization |
| MIC | minimum inhibitory concentration |
| MPS | microphysiological systems |
| MSI | mass spectrometry imaging |
| Papp | apparent permeability coefficient |
| PBPK | physiologically based pharmacokinetic |
| PD | pharmacodynamics |
| PDMS | polydimethylsiloxane |
| PK | pharmacokinetics |
| PXR | pregnane X receptor |
| RIF | rifampicin |
| SILAC | stable isotope labeling by amino acids in cell culture |
| t1/2 | elimination half-life |
| Tmax | time to maximum concentration |
| UGT1A1 | uridine 5′-diphospho-glucuronosyltransferase 1A1 |
| VD3 | vitamin D3 |
| Vd | volume of distribution |
| VDR | vitamin D receptor |
| γH2AX | phosphorylated histone H2AX |
| DDI | drug–drug interaction |
| PBBM | physiologically based biopharmaceutics modeling |
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