IS	Ischemic stroke
TCA	Tricarboxylic acid
Fe-S cluster	Iron–sulfur clusters
DALYs	Disability-adjusted life years
ATP	Adenosine triphosphate
ROS	Reactive oxygen species
BBB	Blood–brain barrier
ER	Endoplasmic reticulum
CTR1	Copper transporter 1
CCS	Copper chaperone for superoxide dismutase
SOD1	Superoxide dismutase 1
ATOX1	Antioxidant 1 copper chaperone
ATPases	Adenosine triphosphatases
ATP7A	ATPase copper transporting alpha
ATP7B	ATPase copper transporting beta
TGN	Trans-Golgi network
MT	Metallothionein
GSH	Glutathione
COX17	Cytochrome c oxidase assembly protein 17
COX	Cytochrome c oxidase
SLC31A1	Solute carrier family 31 member 1
FDX1	Ferredoxin 1
LIAS	Lipoyl synthase
HSP70	Heat shock protein 70
DLAT	Dihydrolipoamide S-acetyltransferase
DLST	Dihydrolipoamide S-succinyltransferase
RAB18	Ras-related protein Rab-18
CPT1A	Carnitine palmitoyltransferase 1A
DLD	Dihydrolipoamide dehydrogenase
PPP1R15A	Protein phosphatase 1 regulatory subunit 15A
PP1	Protein phosphatase 1
4EBP1	Eukaryotic translation initiation factor 4E-binding protein 1
G6PD	Glucose-6-phosphate dehydrogenase
CREB	cAMP response element-binding protein
BDNF	Brain-derived neurotrophic factor
I/R	Ischemia/reperfusion
MCAO/R	Middle cerebral artery occlusion/reperfusion
METTL14	Methyltransferase-like 14
TTM	Tetrathiomolybdate
CAA	Cerebral amyloid angiopathy
Aβ	Amyloid-β
Dex	Dexmedetomidine
EDB	Edaravone dextrose
MCAO	Middle cerebral artery occlusion
OGD/R	Oxygen–glucose deprivation/reperfusion
SLC7A11	Solute carrier family 7 member 11
8HQs	8-Hydroxyquinolines
ZnPT	Zinc pyrithione
TCM	Traditional Chinese medicine
ACO2	Aconitase 2
AS	Astragaloside IV
DUSP1	Dual specificity phosphatase 1
PHB2	Prohibitin 2
MQC	Mitochondrial quality control
CG	Calycosin-7-O-β-D-glucoside
AR	Astragali Radix
GSK-3β	Glycogen synthase kinase 3β
ATF3	Activating transcription factor 3
PHI	Phillygenin
ART	Artesunate
MyD88	Myeloid differentiation primary response 88
NF-κB	Nuclear factor-kappa B
MT2A	Metallothionein 2A
XFC	Xinfeng Capsule
METTL3	Methyltransferase-like 3
miR-221/222-3p	MicroRNA-221/222-3p
TLB	Trilobatin
DIC	Doxorubicin-induced cardiotoxicity