ABCD4	Subfamily D member 4
AdoCbl	Adenosylcobalamin or cobamamid
AMD	Age-associated macular degeneration
ATP	Adenosine triphosphate
$\alpha$-CD	alfa-ciclodextrina
BHMT	Betaine-homocysteine methyltransferase
$\beta$-CD	beta-ciclodextrina
Ca2+	Calcium ion (2+)
Cbl	Vitamin B12 or cobalamin
CblC	Homocystinuria type C
CBS	Cystionin beta-synthase
CD	Cyclodextrina
CSF	Cerebrospinal fluid
CMC	Critical micellar concentration
CN-Cbl	Cyanocobalamin
Co	Cobalt
CSE	Cystationine beta-lyase
DED	dry eye disease
DHF	Dihydrofolate
DNA	deoxyribonucleic acid
Fe	Iron
γ-CD	gammaciclodextrina
H+	Hydrogen ion
Hb	Hemoglobin
HC	Haptocorrin
HCb	Hydroxocobalamin
HCO3−	Ion bicarbonate
Hcy	Homocysteine
HPβCD	hidroxipropil-beta-ciclodextrina
HPγCD	hidroxipropil-gamma-ciclodextrina
IDDSs	Implantable drug delivery systems
IF	Intrinsic factor
IFN-2	Interferon-2
IM	Intramuscular
IOP	Intraocular pressure
IV	Intravenous
LMBD1	Membrane receptor domain 1
MA	Methylmalonic acid
MCA	Monochloroacetic acid
MeCbl	Methylcobalamin
Met	Methionine
Me-THF	N5-methyltetrahydrofolate
Mg2+	Magnesium ion (2+)
MMA	Methylmalonic aciduria
MMACHC	Methylmalonic aciduria protein type CblC with homocistinuria
MMADHD	Methylmalonic aciduria protein type CblD with homocistinuria
MMC	Methylmalonyl-CoA
MS	Methionine synthase
MTHFR	Methylentetrahydrofolate reductase
MTR	Enzyme methyltransferase
MUT	Enzyme methylmalonyl-CoA mutase
NH4+	Ammonium ion
NLCs	nanostructured lipid carriers
NMDA	N-mettyl-D-aspartate
PAMAM	Hydroxyl-terminated polyamidoamine
PCL	Poly-e-carprolactone
PCR	Polymerase chain reaction
PLA	Poly(l-lactide)
PLGA	Poly(lactic-co-glycolic acid)
PLN	Hybrid nanoparticles o lipid-polymer nanoparticle
P407	Poloxamer-407
RPE	Retinal pigment epithelium
RTM	Renal thrombotic microangiopathy
ROS	Reactive oxygen species
SAHH	S-adenosyl-L-homocysteine hidrolase
SAH	S-adenosylhomocysteine
SAM	S-adenosimethionine
SC	Subcutaneous
SLN	solid lipid nanoparticles
Suc-CoA	Succinyl-CoA
TC-I	Transcobalamin I o transcobalamin $\alpha$
TC-II	Transcobalamin II
TDDS	Transdermal drug delivery system
THF	Tetrahydrofolate
TPGS	Polyethylene D-alpha-tocopherol glycol 1000 succinate
VEGF	vascular endothelial growth factor