GZFL	Guizhi Fuling Capsule
TCM	Traditional Chinese Medicine
PGF2α	prostaglandin F2α
PGE2	prostaglandin E2
NF-κB	nuclear factor kappa B
IKKβ	IκB kinase β
COX-2	cyclooxygenase-2
iNOS	inducible nitric oxide synthase
PK-PM-PD	pharmacokinetic–pharmacometabolomic–pharmacodynamic
EI	Efficacy Index
MEI	Metabolite–Efficacy Index
UPLC/Q-TOF-MS	ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
DINA	diagnostic ion network analysis
PPI	protein–protein interaction
PCA	principal component analysis
PLS-DA/OPLS-DA	(orthogonal) partial least squares-discriminant analysis
KEGG	Kyoto Encyclopedia of Genes and Genomes
GO	Gene Ontology
ROC	receiver operating characteristic
AUC	area under the curve
VIP	variable importance in projection
GZFL-L/GZFL-H	GZFL low-dose/high-dose
QC	quality control
H&E	hematoxylin and eosin
β-EP	β-endorphin
NO	nitric oxide
TNF-α	tumor necrosis factor-alpha
IL-6/IL-1β/IL-10	interleukin-6/-1β/-10