| CDK | cyclin-dependent kinase |
| CRC | colorectal cancer |
| EMT | epithelial–mesenchymal transition |
| ESI | electrospray ionization |
| γ-H2AX | phosphorylated histone H2AX |
| HELLS | helicase lymphoid-specific |
| ΔΨm | mitochondrial membrane potential |
| PARP | poly(ADP-ribose) polymerase |
| siControl | non-targeting control small interfering RNA |
| siHELLS | HELLS-targeting small interfering RNA |
| UPLC-QTOF/MS | ultra-performance liquid chromatography–quadrupole time-of-flight mass spectrometry |
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