Ctx	Ceftriaxone
TDDS	Targeted drug delivery systems
RBC-Ctx	Ceftriaxone encapsulated in autologous erythrocytes
Free-Ctx	Free ceftriaxone
RBC	Red blood cell
IL-1β	Interleukin-1β
IACUC	Institutional Animal Care and Use Committee
r	Correlation coefficient
LOD	Limit of detection
LOQ	Limit of quantification
RSD	Relative standard deviation
HPLC	High-performance liquid chromatography
HPLC-UV	High-Performance Liquid Chromatography-Ultraviolet
k12 and k21	Intercompartmental transfer rate constants
Vss	Steady-state volume of distribution
Vd	Apparent volume of distribution
T/P ratio	Tissue-to-plasma concentration ratio
PBS	Phosphate-buffered saline
mean ± SD	Mean ± standard deviation
ESR	Erythrocyte sedimentation rate
AUC0–∞	Area under the concentration–time curve extrapolated to infinity
AUC0–tlₐst	Area under the concentration–time curve up to the last measurable point
C0	Initial concentration
CL	Clearance
C_last	Last measured concentration
C_max	Maximum concentration
T½	Elimination half-life
k_el	Elimination rate constant
MRT0–∞	Mean residence time