| 2-DG |
2-Deoxyglucose |
| AML |
Acute Myeloid Leukemia |
| AMPK |
AMP-Activated Protein Kinase |
| ATF4 |
Activating Transcription Factor 4 |
| ATP |
Adenosine Triphosphate |
| AZD3965 |
Monocarboxylate Transporter 1 Inhibitor |
| BAY-876 |
Glucose Transporter 1 Inhibitor |
| BCL-2 |
B-Cell Lymphoma 2 |
| BIM |
BCL-2 Interacting Mediator of Cell Death |
| BSO |
Buthionine Sulfoximine |
| CB-839 |
Telaglenastat (Glutaminase Inhibitor) |
| CBF |
Core-Binding Factor |
| CDA |
Cytidine Deaminase |
| CHOP |
C/EBP Homologous Protein |
| CI |
Combination Index |
| CPI-613 |
Devimistat |
| CPT1 |
Carnitine Palmitoyltransferase 1 |
| DNA |
Deoxyribonucleic Acid |
| dNTP |
Deoxyribonucleoside Triphosphate |
| FAO |
Fatty Acid Oxidation |
| FLT3 |
FMS-Like Tyrosine Kinase 3 |
| FLT3-ITD |
FMS-Like Tyrosine Kinase 3 Internal Tandem Duplication |
| GCN2 |
General Control Nonderepressible 2 Kinase |
| GLS1 |
Glutaminase 1 |
| GLUT1 |
Glucose Transporter 1 |
| GSH |
Glutathione |
| GSK3
|
Glycogen Synthase Kinase 3 Beta |
| HSPCs |
Hematopoietic Stem and Progenitor Cells |
| IC50
|
Half-Maximal Inhibitory Concentration |
| IDH |
Isocitrate Dehydrogenase |
| IDH1/IDH2 |
Isocitrate Dehydrogenase 1/2 |
| IMT1 |
Mitochondrial RNA Polymerase Inhibitor |
| LSC/LSCs |
Leukemic Stem Cell(s) |
| MCL-1 |
Myeloid Cell Leukemia 1 |
| MCT1/MCT4 |
Monocarboxylate Transporter 1/4 |
| NADPH |
Nicotinamide Adenine Dinucleotide Phosphate (Reduced Form) |
| NAMPT |
Nicotinamide Phosphoribosyltransferase |
| NOX |
NADPH Oxidase |
| NRAS |
Neuroblastoma RAS Viral Oncogene Homolog |
| OCR |
Oxygen Consumption Rate |
| OXPHOS |
Oxidative Phosphorylation |
| PHGDH |
Phosphoglycerate Dehydrogenase |
| POLRMT |
Mitochondrial RNA Polymerase |
| ROS |
Reactive Oxygen Species |
| RUNX1 |
Runt-Related Transcription Factor 1 |
| TCA |
Tricarboxylic Acid (Cycle) |
| TET2 |
Tet Methylcytosine Dioxygenase 2 |
| TP53 |
Tumor Protein p53 |
| TrxR |
Thioredoxin Reductase |
|
Mitochondrial Membrane Potential |