αSyn-SAA	α-Synuclein seed amplification assay
Aβ	Amyloid-β
AADC	Aromatic L-amino acid decarboxylase
AI	Artificial intelligence
BBB	Blood–brain barrier
BPND	Binding potential relative to the non-displaceable compartment
CBS	Corticobasal syndrome
CNN	Convolutional neural network
COMT	Catechol-O-methyltransferase
CSF	Cerebrospinal fluid
CT	Computed tomography
D1/D5	Dopamine D1/D5 receptor subtypes
D2/D3	Dopamine D2/D3 receptor subtypes
DAT	Dopamine transporter
DLB	Dementia with Lewy bodies
DMFP	Desmethoxyfallypride
DTBZ	Dihydrotetrabenazine
EANM/SNMMI	European Association of Nuclear Medicine/Society of Nuclear Medicine and Molecular Imaging
FDG	Fluorodeoxyglucose
FDOPA	6-Fluoro-L-DOPA
FMT	6-Fluoro-L-m-tyrosine
GBA1	Glucosylceramidase beta 1
GPCR	G protein-coupled receptor
HC	Healthy control
IBZM	Iodobenzamide
iRBD	Isolated rapid eye movement sleep behaviour disorder
Ki	Influx constant
L-DOPA	L-3,4-Dihydroxyphenylalanine
LAT1	Large neutral amino acid transporter type 1
LRRK2	Leucine-rich repeat kinase 2
MAO	Monoamine oxidase
MIBG	Metaiodobenzylguanidine
ML	Machine learning
MRI	Magnetic resonance imaging
MSA	Multiple system atrophy
MSA-C	Multiple system atrophy with predominant cerebellar ataxia
MSA-P	Multiple system atrophy with predominant parkinsonism
NET	Noradrenaline transporter
NSD-ISS	Neuronal α-synuclein disease integrated staging system
PD	Parkinson’s disease
PET	Positron emission tomography
PINK1	PTEN-induced kinase 1
PRKN	Parkin RBR E3 ubiquitin protein ligase
PSP	Progressive supranuclear palsy
R1	Relative tracer-delivery parameter
ROI	Region of interest
SBR	Specific binding ratio
SERT	Serotonin transporter
SNpc	Substantia nigra pars compacta
SPECT	Single-photon emission computed tomography
SUVR	Standardised uptake value ratio
SWEDD	Scans without evidence of dopaminergic deficit
SynNeurGe	α-Synuclein pathology, neurodegeneration, and genetics
TH	Tyrosine hydroxylase
TM	Transmembrane
VMAT2	Vesicular monoamine transporter type 2
VOI	Volume of interest