Table V. Clinical-epidemiological, histopathological, immunophenotype, and therapeutic characteristics of mycosis fungoides according to clinical presentation.
*Fisher’s exact test, †Student’s t test, ‡Mann-Whitney U test, §interquartile ranges (25th, 75th percentiles)
|
Classical n = 6 |
Hypopigmented n = 11 |
p-value | |
|---|---|---|---|
|
Age, years, mean (SD)* At diagnosis At referral |
12.6 ± 2.0 11.3 ± 2.2 |
11.5 ± 3.1 10.6 ± 3.2 |
0.43† 0.65† |
| Duration of disease, median (IQR) | 48 (24.0, 75.0) | 24 (24, 48.0) | 0.35‡ |
|
Clinical presentation, present, n (%) Hypochromic patches, n = 11 Erythematous patches + erythematous-scaly plaques, n = 6 |
0 6 (100.0) |
11 (100.0) 0 |
< 0.01* < 0.01* |
|
Symptoms, positive, n (%) Xerosis, n = 12 Pruritus, n = 10 |
6 (100.0) 5 (83.3) |
6 (54.5) 5 (45.5) |
0.10* 0.30* |
|
Histopathology Number of biopsies, n (%) Time to biopsy, months, IQR§ |
2 (1,3) 21 (4.2, 30.0) |
1 (1,2) 6 (3.0, 24.0) |
0.21‡ 0.35‡ |
|
Type of treatment, n (%) Methotrexate, n = 3 Phototherapy, n = 3 Extracorporeal photopheresis, n = 3 |
3 (50.0) 3 (50.0) 0 |
0 0 3 (27.3) |
0.02* 0.02* 0.51* |