TABLE 4.
Nuclear localization during HDV genome replicationa
| Experiment no. (day)b | % δAg | % Genomic δRNA | % Antigenomic δRNA | % 18S rRNA |
|---|---|---|---|---|
| 1 (12) | 27 | 12 | 47 | 8 |
| 2 (12) | 20 | 22 | 53 | 22 |
| 3 (4) | 13 | 28 | 46 | 11 |
| 4 (4) | 20 | 9 | 61 | 13 |
a
The data quantitated are as described for panels A to D in the legend to Fig. 1. Shown are the percentages in the nuclear fraction of total detected δAg, genomic and antigenomic δRNA, and 18S rRNA.
b
These four experiments represent individual fractionations of HuH7 cells transfected, in duplicate, 12 or 4 days previously. Figure 1 shows the data for experiments 1 and 2 only. Quantitation of δAg refers to both small and large forms.