AMSTAR-2	A MeaSurement Tool to Assess Systematic Reviews, Version 2
CI	Confidence interval
EMA	European Medicines Agency
FDA	United States Food and Drug Administration
GMFCS	Gross Motor Function Classification System
GMFM-66	Gross Motor Function Measure, 66-item version
GRADE	Grading of Recommendations, Assessment, Development and Evaluations
IAS	Internal Anal Sphincter
ICF	International Classification of Functioning, Disability and Health
MEDLINE	Medical Literature Analysis and Retrieval System Online
PEDI	Pediatric Evaluation of Disability Inventory
PedMIDAS	Pediatric Migraine Disability Assessment Score
PRISMA	Preferred Reporting Items for Systematic Reviews and Meta-Analyses
RCT	Randomised Controlled Trial
RoB 2	Revised Cochrane Risk-of-Bias Tool for Randomised Trials, Version 2
ROBINS-I	Risk Of Bias In Non-randomised Studies of Interventions
SIPEXI	Sialorrhoea Pediatric Xeomin Investigation Trial