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. 2026 Sep 9;14(9):800. doi: 10.3390/toxics14090800
%AUC percentage area under the curve
cDV0 minimal concentration required to exceed the binary classification in GARDskin (DV ≥ 0)
CNIH confirmation of no induction in human
CP component-based prediction model
DV decision value
GARDskin DR dose–response adaptation of the genomic allergen rapid detection for skin sensitizers
GC–MS gas chromatography–mass spectrometry
GHS Global Harmonized System of Classification and Labeling of Chemicals
HRIPT human repeat insult patch test
LLNA local lymph node assay
LogP logarithm of octanol–water partition coefficient
MW molecular weight
NAM new approach methodology
NCS natural complex substance
NESIL no expected sensitization induction level
nPACds normalized percentage of assessed constituents for dermal sensitization
OECD TG Organisation for Economic Co-operation and Development test guideline
POD point of departure
RI retention index
RIFM Research Institute for Fragrance Materials
SARA-ICE skin allergy risk assessment—integrated chemical environment
WOE weight of evidence