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. Author manuscript; available in PMC: 2006 Feb 7.
Published in final edited form as: Psychol Bull. 2004 Jul;130(4):601–630. doi: 10.1037/0033-2909.130.4.601

Table 6.

Meta-Analysis of Immune Responses to Stressful Event Sequences in Healthy Participants

Immune marker k N r SEr 95% CI p Q
Leukocyte subset count
 Monocytes 3 113 −.02 .10 −.21, .17 .87 0.39
 Lymphocytes 5 223 .05 .07 −.09, .18 .49 2.65
 T lymphocytes 5 213 −.02 .07 −.16, .12 .82 0.37
 T-helper lymphocytes 9 566 .03 .11 −.19, .25 .81 39.29***
 T-cytotoxic lymphocytes 8 544 −.14 .15 −.41, .15 .35 58.22***
 T-helper:T-cytotoxic ratio 6 296 .06 .08 −.09, .21 .44 7.54
 B lymphocytes 5 185 .02 .08 −.13, .17 .76 0.35
 Natural killer cells 4 370 .17 .09 .00, .34 .05 5.06
Leukocyte subset percentage
 T lymphocytes 3 129 .02 .09 −.16, .19 .85 0.11
 T-helper lymphocytes 5 279 .00 .06 −.12, .12 .94 0.00
 T-cytotoxic lymphocytes 5 279 −.05 .06 −.17, .07 .43 3.65
 B lymphocytes 3 129 −.04 .09 −.22, .14 .67 0.57
Specific immunoglobulin
 Epstein-Barr virus 3 198 .21 .07 .07, .34 .003 1.18
Natural killer cell function
 Natural killer cell cytotoxicity 13 698 −.03 .17 −.29, .34 .87 164.40***
Lymphocyte proliferation
 Proliferation to ConA 6 297 −.04 .06 −.15, .08 .53 2.53
 Proliferation to PHA 11 675 .10 .10 −.09, .28 .32 42.25***
 Proliferation to PWM 7 284 .12 .16 −.19, .40 .45 28.72***

Note. CI = confidence interval; ConA = concanavalin A; PHA = phytohemagglutinin; PWM = pokeweed mitogen.

***

p < .001.