Table 2.
Risk of bias assessment.
| SYRCLE’ s risk of bias tool for animal studies | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| References | Sequence generation | Baseline characteristics | Allocation concealment | Random housing | Performance Blinding | Random outcome assessment | Blinding of outcome assessment | Incomplete outcome data | Selective outcome reporting | Other sources of bias |
| Machnicki et al., 2022 | U | Y | U | U | N | U | N | N | U | Y |
| Cao et al., 2010 | U | Y | U | U | N | U | N | N | U | Y |
| Xiao et al., 2010 | U | Y | U | U | N | U | N | N | U | Y |
| Lorincz et al., 2010 | U | Y | U | U | N | U | N | Y | U | Y |
| Cao et al., 2009) | U | Y | U | U | N | U | N | N | U | Y |
| Patsch et al., 2011 | U | Y | U | U | N | U | N | Y | U | Y |
| Gautam et al., 2014 | U | Y | U | U | N | U | N | Y | U | Y |
Y, yes = low risk of bias; N, no = high risk of bias; U, unclear = unclear risk of bias.